Tobacco Leaf Extract Solanesol

Botanical Name: Nicotiana tabacum
Part Used: Leaf
Active ingredients: Solanesol
Appearance: White Powder
Specification: 90% by HPLC
Package: 25kg/drum

What is Tobacco Leaf Extract Solanesol?

Solanesol, which mainly accumulates in solanaceous crops, including tobacco, tomato, potato, eggplant, and pepper plants, is a long-chain polyisoprenoid alcohol compound with nine isoprene units. Chemical synthesis of solanesol is difficult; therefore, solanesol is primarily extracted from solanaceous crops, particularly tobacco leaves. In plants, solanesol exists in both free and esterified forms, and its accumulation is influenced by genetic and environmental factors. Solanesol is widely used in the pharmaceutical industry as an intermediate for the synthesis of ubiquinone drugs, such as coenzyme Q10 and vitamin K2. Solanesol possesses antibacterial, antifungal, antiviral, anticancer, anti-inflammatory, and anti-ulcer activities, and solanesol derivatives also have anti-oxidant and antitumour activities, in addition to other bioactivities. Solanesol derivatives can also be used for the treatment of cardiovascular disease, osteoporosis, acquired immune deficiency syndrome, and wound healing. Solanesol biosynthesis occurs in plastids of higher plants via the 2-C-methyl-d-erythritol-4-phosphate (MEP) pathway. The key enzymes in solanesol biosynthesis, including 1-deoxy-d-xylulose-5-phosphate synthase, 1-deoxy-d-xylulose-5-phosphate-reductoisomerase, isopentenyl pyrophosphate isomerase, and solanesyl diphosphate synthase, are also important regulators of the MEP pathway, and their overexpression is favorable for downstream metabolic flow, further promoting the synthesis of downstream metabolites, such as solanesol. Future studies should determine the pharmacokinetic properties of solanesol and its derivatives and investigate the metabolic pathways and regulatory mechanisms mediating solanesol biosynthesis, metabolic and genetic engineering of solanesol, the synthetic biology of solanesol, and the physiological role of solanesol. In the present review, we systematically summarise current knowledge on solanesol resources, derivatives, bioactivities and medicinal applications, metabolic pathways, and key biosynthetic enzymes.

Health Benefits of Tobacco Leaf Extract Solanesol

1.It can not only be used for the synthesis of Coenzyme Q10 and Vitamin k2, but also for the synthesis of raw materials as an anti-allergic drug, anti-ulcer drug, hypolipidemic drug, and anti-cancer drug.

2.In the field of medicine Coenzyme Q10 is commonly used for the prevention and treatment of cardiovascular system disease, and also has a certain treatment of acute cancer and virus hepatitis.

3.In addition, Coenzyme Q10 has a strong healthcare effect to improve human immunity, maintain skin smoothness, and enhance vitality as well.

Certificate of Analysis

ITEM SPECIFICATION METHOD RESULT
Assay Solanesol 90% HPLC Complies
Appearance White powder N/A Complies
Particle size 100% pass 80 mesh USP32<786> Complies
Extract Solvents Water/Ethanol N/A Complies
Identification Positive Reaction N/A Complies
Tests
Loss on Drying ≤5.0% Eur.Ph.6.0[2.8.17] Complies
Acid-insoluble ash ≤7.0% Eur.Ph.6.0[2.4.16] Complies
Lead(Pb) ≤1.0mg/kg Eur.Ph6.0<2.2.58>ICP-MS Complies
Arsenic(As) ≤1.0mg/kg Eur.Ph6.0<2.2.58>ICP-MS Complies
Cadmium(Cd) ≤1.0mg/kg Eur.Ph6.0<2.2.58>ICP-MS Complies
Mercury(Hg) ≤1.0mg/kg Eur.Ph6.0<2.2.58>ICP-MS Complies
Solvents Residue Meet Eur.Ph6.0<5.4> Eur.Ph 6.0<2.4.24> Complies
Pesticides Residue Negative USP32<561> Complies
Microbiological Control
Total bacterial count ≤1000cfu/g USP30<61> Complies
Yeast & mold ≤100cfu/g USP30<61> Complies
Salmonella Negative USP30<62> Complies
E.Coli Negative USP30<62> Complies

Flowchart of Production

flowchart

Package for Tobacco Leaf Extract Solanesol

packing

Shipping for Tobacco Leaf Extract Solanesol

  • By Express: Suitable for under 50kg, 5-10 days
  • By Air: Suitable for more than 50kg, 7-15 days
  • By Sea: Suitable for more than 500kg, 15-45days

Why Choose FYZ Tobacco Leaf Extract Solanesol?

  • FYZ is a professional Tobacco Leaf Extract Solanesol manufacturer in China, provides OEM service.
  • FREE SAMPLE with freight collection (5-10g) for detection, if you need more, please contact us.
  • Fast delivery by DHL/FedEx, air as your requirement.
  • All of our products from nature, no additive.
  • Money refund policy.

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