Agastache Rugosa Extract

Botanical Name: agastache rugosa extract
Part Used: Leaf
Active ingredients: Pachypodol, Methylchavicol
Appearance: Brown Powder
Specification: 10:1
Package: 25kg/drum

What Is Agastache Rugosa Extract?

Agastache rugosa, known as Korean mint, blue licorice, purple giant hyssop, Indian mint, wrinkled giant hyssop, is an aromatic herb in the mint family, native to East Asia (China, Japan, Korea, Russian Primorye, Taiwan, and Vietnam).

Agastache rugosa is an herbal medicine that has been used for the treatment of diverse kinds of symptoms in traditional medicine. This work was undertaken to assess the protective properties of A. rugosa leaves against UV-B-induced photoaging in HaCaT keratinocytes. They were evaluated via analyzing reactive oxygen species (ROS), promatrix metalloproteinase-2 (proMMP-2) and -9 (proMMP-9), total glutathione (GSH), total superoxide dismutase (SOD), cellular viability, flavonoid content and in vitro radical scavenging activity. Total flavonoid content of ARE, agastache rugosa extract, was 22.8±7.6mg of naringin equivalent/g ARE. ARE exhibited ABTS(+) radical scavenging activity with an SC50 of 836.9μg/mL. ARE attenuated the UV-B-induced ROS generation. It diminished the UV-B-induced elevation of proMMP-2 and -9 at both activity and protein levels. On the contrary, ARE was able to enhance the UV-B-reduced total GSH and total SOD activity levels. ARE, at the used concentrations, was unable to interfere with the cellular viabilities of HaCaT keratinocytes under UV-B irradiation. Taken together, ARE possesses a protective potential against UV-B-induced photoaging in HaCaT keratinocytes, possibly based upon up-regulating antioxidant components, including total GSH and SOD. These findings reasonably suggest the use of agastache rugosa extract as a photoprotective resource in manufacturing functional cosmetics.

Chemical Constituents of Agastache Rugosa

Chemical compounds found in the plant include:

  • Estragole, plant
  • p-Anisaldehyde, plant
  • 4-methoxycinnamaldehyde, shoot
  • Pachypodol, leaf
  • Methylchavicol (60.01-88.43%),
  • d-Limonene
  • Caryophyllene
  • Hexadecanoic acid
  • Linoleic acid
  • Octahydro-7-methyl-methylene-4-(1-methylethyl)-1H-cyclopenta[1,3]cyclopropa[1,2]benzene

Medicinal Use of Agastache Rugosa Extract

As one of the 50 fundamental herbs, agastache rugosa is known as huò xiāng. These plants provide the materia medica, or basis, for traditional Chinese medicine. Considered to be a “warming” herb, it is used in situations where there is “dampness” within the digestive system, resulting in poor digestion and reduced vitality. The leaves and stems are antibacterial, antifungal, aromatic, carminative, diaphoretic, febrifuge and stomachic. They are used internally to improve the appetite and strengthen the digestive system, they relieve symptoms such as abdominal bloating, indigestion, nausea and vomiting. They are also used to treat morning sickness. The leaves are also used in the treatment of chest congestion, diarrhoea and headaches. An infusion of the leaves is used in the treatment of angina pains. The plant is used as a folk remedy for cancer, extracts of the plant have shown anticancer activity.

Certificate of Analysis

Assay 10:1 UV Complies
Appearance Brown N/A Complies
Particle size 100% pass 80 mesh USP32<786> Complies
Extract Solvents Water/Ethanol N/A Complies
Identification Positive Reaction N/A Complies
Loss on Drying ≤5.0% Eur.Ph.6.0[2.8.17] Complies
Acid-insoluble ash ≤7.0% Eur.Ph.6.0[2.4.16] Complies
Lead(Pb) ≤1.0mg/kg Eur.Ph6.0<2.2.58>ICP-MS Complies
Arsenic(As) ≤1.0mg/kg Eur.Ph6.0<2.2.58>ICP-MS Complies
Cadmium(Cd) ≤1.0mg/kg Eur.Ph6.0<2.2.58>ICP-MS Complies
Mercury(Hg) ≤1.0mg/kg Eur.Ph6.0<2.2.58>ICP-MS Complies
Solvents Residue Meet Eur.Ph6.0<5.4> Eur.Ph 6.0<2.4.24> Complies
Pesticides Residue Negative USP32<561> Complies
Microbiological Control
Total bacterial count ≤1000cfu/g USP30<61> Complies
Yeast & mold ≤100cfu/g USP30<61> Complies
Salmonella Negative USP30<62> Complies
E.Coli Negative USP30<62> Complies

Flowchart of Production


Package for Agastache Rugosa Extract


Shipping for Agastache Rugosa Extract

  • By Express: Suitable for under 50kg, 5-10 days
  • By Air: Suitable for more than 50kg, 7-15 days
  • By Sea: Suitable for more than 500kg, 15-45days

Why Choose FYZ Agastache Rugosa Extract?

  • FYZ is a professional Agastache Rugosa Extract manufacturer in China, provides OEM service.
  • FREE SAMPLE with freight collection (5-10g) for detection, if you need more, please contact us.
  • Fast delivery by DHL/FedEx, air as your requirement.
  • All of our products from nature, no additive.
  • Money refund policy.